Detailed Test Information

DNA Oestrogen

Key Advantages

test background

What is DNA Oestrogen? Oestrogen hormones affect the growth, differentiation and function of a number of target tissues. Improving oestrogen metabolism is of benefit to women who suffer from oestrogen-dominant conditions such as endometriosis, premenstrual syndrome and uterine fibroids tumours, or where there is a family history of breast, uterine or ovarian cancer, or prostate cancer in men. 

The importance of both oestrogen and progesterone in breast cancer development is well established. However, considerable inter-individual variability has been observed in carcinogen metabolism, metabolism of steroid hormones, and phase I and phase II detoxification.  

Variations in genes involved in these biological processes help identify a sub-population of women and men with higher lifetime exposure to oestrogens, oestrogen metabolites and other carcinogens.

clinical value

Understanding an individual’s genetic variability will allow for targeted diet, lifestyle and hormone intervention optimisation.  

The results provide unique information to guide personalised diet, lifestyle, hormone and nutraceutical recommendations. 

The DNA Oestrogen report has 4 main components:

  1. Summary of gene results 
  2. Oestrogen metabolism and detoxification pathway infographic 
  3. Gene and genotype specific content 
  4. Nutrition guidelines for improving oestrogen metabolism 

DNA Oestrogen provides the genotype result of the client and, when there is a variant detected that leads to a change in how it may affect an individual’s oestrogen metabolism and health, a description of the relevance of the variant will be given. Actionable, genotype specific information to intervene appropriately is also given.

Key Assessments Included:

CYP1A1  
CYP1B1  
CYP17A  
MnSOD  
GSTM1  
GSTT1  
COMT  
MTHFR  
SULT1A1  
NQ01  
FACTOR V

Related Tests

What is DNA Oestrogen?

Oestrogen hormones affect the growth, differentiation and function of a number of target tissues. Improving oestrogen metabolism is of benefit to women who suffer from oestrogen-dominant conditions such as endometriosis, premenstrual syndrome and uterine fibroid tumours, or where there is a family history of breast, uterine or ovarian cancer, or prostate cancer in men.

The importance of both oestrogen and progesterone in breast cancer development is well established. However, considerable inter-individual variability has been observed in carcinogen metabolism, metabolism of steroid hormones, and phase I and phase II detoxification.

Cumulative exposure to oestrogen has been shown to have a high correlation to the development of breast cancer.

Variations in genes involved in these biological processes help identify a sub-population of women and men with higher lifetime exposure to oestrogens, oestrogen metabolites and other carcinogens. Understanding an individual’s genetic variability will allow for targeted diet, lifestyle and hormone intervention.

The results provide unique information to guide personalised diet, lifestyle, hormone and nutraceutical recommendations. If you are interested in incorporating this test into your practice please contact us for more information.

Resources

About DNALife​

DNALife comprises a dedicated team of scientists with expertise in Human Genetics, Molecular Biology, Nutritional Genomics and Dietetics. By placing emphasis on the inter-relationship between genes, nutrition and lifestyle, genetic tests provide a valuable tool for the management of health and wellness. The use of cutting-edge molecular technologies provides high-quality testing, performed according to the highest international standards.

Equipped with the most up-to-date DNA tests, DNALife is dedicated to providing healthcare practitioners with training and education to accurately and usefully interpret genetic results.

The Importance of Lab Transparency

How to Ensure your Functional Tests are Evidence-Based

It is important to be informed as to where tests are being conducted as well as the technology used, so that you can be confident that your patients are performing evidence-based tests. RN Labs has always insisted in choosing laboratories that are of the highest standard globally with evidence-based functional tests, thereby improving patient outcomes and supporting the industry as a whole. RN Labs believes in maintaining full transparency of who and where your test is being carried out, so that you can make fully informed decisions with your patients.

S QLD / N NSW Area Manager

Jessica Morland

Jess is a qualified Nutritionist with a Bachelor of Health Science in Nutritional Medicine. She believes that there is no one size fits all approach and is passionate about educating, inspiring and supporting clients and practitioners with a customised approach to healthcare. Specialties include preconception, pregnancy, post-natal and infant care. 

Jess is excited to build relationships, educate and share her knowledge with both retail and practitioners in South Queensland and Northern NSW.

Lauren Matich, BHSc (Nat.)

Lauren Matich

BHSc (Nat.)

Lauren is an NHAA accredited Clinical Naturopath with a Bachelor of Health Science. She is incredibly passionate about natural health and educating clients on the foundational importance of nutrition, lifestyle and stress management and believes complimenting these building blocks with nutraceutical support and functional testing often holds the key to optimal health and vitality. Lauren looks forward to supporting practitioners and clients in these key areas.

Specialties include supporting thyroid health, digestive disorders and mental health.