Latest Newsletter (Jun-Jul-19)

NEW! Introducing Online Patient Product Ordering!

How does it work?

1. Practitioner Authorisation

Click Authorise Products for Patient which can be found (when logged in) from the Practitioner Access section of this website.
Enter patient name and email, select the products they have access to and ‘Create Order’.

2. Patient Order & Delivery

Your patient will instantly receive a secure link by email, to select from their personalised products list, complete delivery & payment information, and submit the order. The products are delivered by courier direct to your patient’s door within 5 working days.

3. Practitioner Rebate

You will a receive the difference between wholesale & RRP (30%) on all patient product orders as a monthly rebate. This can be offset to your RN Labs invoices, or deposited into your bank account on a monthly basis.
As well as being able to view details of your patient orders from your online dashboard, you will also be emailed a monthly summary of patient activity containing your monthly rebate amount.


Important notes

It remains the practitioner’s duty of care to oversee what products your patients have access to. Each patient has ongoing access to their prescribed products, until amended by you. Product access can be edited quickly and easily from your patient ordering dashboard – which takes effect for your patient immediately.
It remains the practitioner’s duty of care to advise your patients on dose and why they are taking the prescribed product/s. Patients who contact RN Labs with technical (non-admin) questions will be referred back to their practitioner. Please ensure you are available to your patient for any such enquires.

The Power of Choline for Methylation

Many practitioners are aware that Betaine (aka Trimethylglycine, TMG) is the methyl donor in the BHMT pathway and as it’s alternate name suggests, possesses three chemically reactive methyl groups linked to a nitrogen atom.

Within the BHMT pathway, Betaine is converted into Dimethylglycine (DMG) after donating one of its three methyl groups to homocysteine, to convert it to methionine and ultimately SAMe as an alternate and important route of methylation production to the well known Folate/B12 requiring MTR pathway.

What many practitioners may not be aware of, is that Betaine can be readily produced in the body through the oxidation of Choline via the choline dehydrogenase and betaine aldehyde dehydrogenase enzymes, particularly in the liver and muscles.

For this reason Choline has also been shown to indirectly support homocysteine methylation.

One study of postmenopausal women showed that Choline supplementation increased plasma Betaine levels and slightly lowered plasma levels of total homocysteine (tHcy) after six weeks.

The upper tolerable limit for Choline in adults is 3.5 g/day. Beyond the diet and supplements, the only other source of choline is via de novo synthesis from phosphatidylcholine which requires significant amounts of SAMe via the PEMT pathway (3 mole SAM to produce 1 mole choline) and produces homocysteine.

A deficiency of Choline will therefore put an increased additional burden on potentially already strained SAMe/Methylation levels, in those exhibiting insufficient methylation capacity.

Available evidence suggests that Folate deficiency can be partly compensated for when more Choline is available, and vice versa.

For example, Choline and Phosphatidylcholine were depleted in the livers of rats fed a Folate-deficient diet. In turn, consumption of a Choline-deficient diet decreased hepatic Folate stores and lowered Methionine formation in animal livers by 20%–25%,7 due to less Choline being available for conversion into Betaine. The effects of Choline deficiency on reducing liver SAMe (by 60%) and increasing liver SAH (by 50%) were pronounced.

Supplementation with Choline can therefore prove to be an invaluable if not essential co-prescription with any methylated B vitamins in the clinical treatment of methylation insufficiencies.

Supplements that include the preferable form ‘Choline Dihydrogen Citrate’ in combination with methylated Folate and B12, such as RN Labs’s Methyl Fortify, may provide maximum utility in patients requiring comprehensive methylation support.

References

Methyl Fortify

A balanced and synergistic blend of methylation-supportive B vitamins

Methyl Fortify contains methylfolate (L-5MTHF), methyl-B12, and choline, each serving as an external source of methyl (CH3) groups to the body.

  Provides the externally methylated forms of folate and vitamin B12
  Activated forms of vitamin B2 and B6 provide crucial co-factor support for the proper metabolism of folate, B12 and methylation
  Provides a therapeutic dose of choline for support of the alternate BHMT homocysteine methylation pathway


Sublingual Hydroxy B12

A pure and hypoallergenic form of vitamin B12

Delivered in a stable, great-tasting, and highly-absorbable lozenge that won’t over-stimulate even the most sensitive patients, when taken at appropriate doses, whilst effectively supporting clinically focused vitamin B12 needs.

  Converts to methyl-B12 in the body, without introducing external methyl groups
  Supports the methylation cycle without over-stimulation
  Supports energy production and reduced fatigue
  Ideal for those with specific vitamin B12 needs, such as: in digestive conditions, the elderly, and vegetarian diets
  Supports normal stress and cognitive function through healthy neurotransmitter production
  Great-tasting, sugar-free formula, provides oral health benefits


JUNE – JULY 2019 SPECIAL

Buy 2 or more Methyl Fortify & 2 or more Sublingual B12 in the 1 order, get 20% OFF


*Minimum order 2x Methyl Fortify AND 2x Sublingual Hydroxy B12 (=4 products) to be eligible for the discount. Special applies to mentioned products only.

Example Case Studies

“Wired but Tired”

A 35 year old woman presented with extreme tiredness and fatigue, alongside anxiety. She had noticed that she often felt “wired but tired” which was resulting in sleep onset issues as well.

Treatment

The patient was prescribed 100mg of 5-HTP at rising and retiring.

Outcome

The patient was reviewed after two weeks of treatment and it was found that her anxiety had significantly lowered. She also mentioned that her sleep had been more restful which had resulted in her feeling more refreshed and less fatigued. However, she wanted to reduce her fatigue further. For future treatment, diet and other nutritional deficiencies are being reviewed.

Mechanism of Action

5-HTP is the direct precursor of Serotonin. Serotonin is primarily researched to be affective in mood, appetite and sleep regulation, among numerous other physiological actions.  It is likely that increasing Serotonin levels resulted in reduced anxiety and fatigue for the patient.

“Constant Back Pain”

A 48 year old man presented with persistent lower back pain. He had recently modified his sitting arrangements in his car and at work, however was still having to take OTC NSAIDS 3-5x per week. He considered the pain a major obstacle in his daily tasks and sleep.

Treatment

The patient was prescribed 1000 mg of DL-Phenylalanine 1-2x daily as required.

Outcome

After two weeks the patient had experienced a noticeable reduction in pain, which allowed him to reduce his NSAID use to once or twice a week. The patient was also planning to engage a physiotherapist and commence physical therapy to address the functional causes for the pain.

Mechanism of Action

A potential mechanism in the pain relieving effect of DL-Phenylalanine is through its impact on Enkephalins. Enkephalins are endogenous analgesics that result in decreased sensation of pain upon binding to the opioid receptors. DL-Phenylalanine is hypothesised to block degradation, resulting in increased levels of Enkephalins, without the risks of addiction associated with pharmaceutical opioids.

JUNE – JULY 2019 SPECIAL

30% OFF 5-HTP

JUNE – JULY 2019 SPECIAL

30% OFF DL-Phenylalanine

Top 3 Antibody FAQs

#1 – Which Test to Choose?

Great Plains Food Antibody + Candida
IgG + Candida  (via blood-spot or blood draw)

This test is a cost effective way to reliably test IgG(1-4) reactions and, like the Dunwoody test, includes the added benefit of including a Candida marker. The easy blood-spot collection means this test may be a preferred option for some patients. (Price: $254)

Dunwoody Labs IgG + Complement (C3d)
IgG + Candida + C3d  (via blood-draw)

This test provides the highest level of insight into IgG food reactivity since it not only tests IgG(1-4), but also Complement 3d. Measurement of Complement 3d directly demonstrates the foods causing inflammatory activity. (Price: $365)

#2 – What’s More Relevant: IgA or Complement (C3d)?

IgA = Potential future reactivity
IgA may uncover ‘hidden’ sensitivities.

Elevated IgA (without elevated IgG) indicates that the food has the potential to become to an IgG reaction / food sensitivity in the future.
Dunwoody’s salivary IgA test ($239) may be prescribed alongside any of our Food Antibody test options.

C3d = Present Inflammation
Complement is a quantifiable biomarker of tissue inflammation.

Complement provides you with reliable insight as to what extent food reactions are occurring in the present moment.
For more information on complement you can watch a short video on complement here.

#3 – Dried Blood Spot Or Blood Draw?

Both are equally valid collection options
Confirmed by Validity Testing

RN Labs only works with laboratories that have conducted extensive validity testing and calibrations to ensure appropriate congruence between collection methods (so that either method correlates reliably).

JUNE – JULY 2019 SPECIAL

20% OFF THE GREAT PLAINS IgG plus Candida Food Antibody Test


20% OFF DUNWOODY LABS IgG plus Complement Dietary Antigen Test

When to Recommend a Higher DHA Omega-3?

The omega-3s EPA and DHA occur together in nature, but each plays a distinct role in maintaining health.

Omega-3 DHA is the most abundant omega-3 fatty acid in the brain. DHA has been shown to support a healthy brain and nervous system, aid in cellular fluidity and visual function, and support learning, language abilities, positive mood & emotional well-being. Both EPA and DHA cannot be produced by the body and must be obtained through diet and/or supplements.

DHA: Cognition, Memory & Mood

  • Supports learning, mood & nervous system health
  • Supports the brain, eyes & immune system
  • Essential for proper brain development in infants & children
  • Recommended by physicians for pregnant & lactating women

EPA: Healthy Heart, Joints, Mood & Immunity

  • Maintains a healthy heart & circulatory system
  • Supports joint comfort & mobility
  • Promotes healthy immune function
  • Supports positive mood & wellbeing

Most types of fish oil are higher in EPA than DHA, but Arctic cod liver oil has a higher DHA to EPA ratio.

The ultimate wholefood, Arctic cod liver oil also provides naturally occurring vitamins A
(in cis-retinol form) and D3 in an ideal combination for immune, gut, bone, skin and vision support.

In addition to the naturally-occuring vitamins, Nordic Naturals Arctic-D Cod Liver Oil™ includes an additional 1000 IU of vitamin D3 – perfect for providing additional support during the winter months.

Unlike other cod liver oils on the market, Nordic Naturals Arctic-D Cod Liver Oil™ is made exclusively from 100% wild caught, Norwegian Arctic cod.

JUNE – JULY 2019 SPECIAL

Buy 5 Arctic-D CLO in the one order, get a 6th FREE

Get Better Digestive Results: The Importance of pH

Whether a person is acidic or alkaline, our enzymes are active in every range of the human body.

Enzymes function most efficiently within particular pH ranges throughout the body. This is because enzymes break down specific molecular bonds in food.

For example, a single protease may break down three bonds of a protein, while a blend of four proteases may break down a total of nine bonds. Greater break down of proteins means better digestion and absorption of foods.

In order to be most effective and fast-acting, enzyme formulas should have enzymes that work in a wide range of pH levels that naturally occur in the digestive tract.

Enzymedica developed a Thera-blend™ process for four main types of enzymes —protease, amylase, lipase and cellulase. Thera-blending allows these enzymes to work across the board in a pH range of 2-12.

Thera-blend® has the right blend of enzymes to work throughout the entire digestive system, allowing for more complete digestion of a broad spectrum of foods.

Enzymedica products are 100% vegan & plant-based, blended to provide digestive support throughout the entire digestive tract. They contain no dairy, egg, salt, sucrose, soy, wheat, yeast, nuts, casein, rice, artificial colours, flavours or fillers.

JUNE – JULY 2019 SPECIAL

Buy 2 Digest Premium, get 1 Intolergest HALF PRICE

Notices

NEW COMPOUND RESOURCE

We now have an example of how to complete the MANUAL worksheet for formulating compounds. Click here to view the resource and scroll down to the 3rd page for the example.

For more information on learning how to compound, please see the Nutritional Compounding 101 webinar on our Education Portal.



ARCTIC CLO SUPPLEMENT PANEL CHANGES

Due to FDA regulation changes in the U.S., the following label changes are being applied to the Nordic Naturals Arctic Cod Liver Oil liquid:

  1. The vitamin A on will no longer be listed within a range on the supplement fact panel, instead being listed as a single value.
  2. Vitamin D is no longer included in the supplement facts.
    Each teaspoon still contains anywhere from 0-20 I.U., depending on the natural seasonal variants of the fish caught. This synergistic combination of vitamins as a natural wholefood source is a key benefit of choosing genuine and pure Arctic Cod Liver Oil.
  3. Both vitamins A & D will be listed as mcg (instead of IU) due to new units of measure as specified by the FDA.

Changes only apply to the liquid products (USA labels) and do not apply to the Arctic Cod Liver Oil soft-gels (Australia labels). For more information click here.

Nordic Naturals Arctic Cod Liver Oil is made from 100% wild Arctic cod. No fish body oils or synthetic vitamins or additives are ever used.


ARE YOU BASED IN WESTERN AUSTRALIA?

You can now have your email enquires answered more efficiently by contacting our Perth office directly. Email Support.WA@RNLabs.com.au


NUZEST DISCONTINUED PRODUCTS

Nuzest have informed us that Kids Good Stuff and Just Fruit & Veg product ranges have been discontinued. An email has been sent out to all purchasers of these products. If you missed the memo or want further information please contact our office.


AUTHORISE A TEST UPDATE

You may notice some slight changes in the layout of the Authorise a Test page on RNlabs.com.au – we have made some improvements to help streamline the order flow. In addition, we have added the ability to view your past test authorisations, and the option to switch off email notifications when your patient has completed their test kit order.


FUNCTIONAL TESTING LAB STANDARDS

Have you ever wondered what sets some laboratories apart from others, or what testing standards ensure accurate and quality testing?
Click here for our article on testing standards, so you can make fully informed choices on the labs you choose for your patient tests.


RN LABS EMAIL ADDRESSES

While our old email addresses are currently being redirected to our new email inboxes, please be aware that eventually, all @researchnutrition.com.au email addresses will become inactive. Therefore, when emailing us, we kindly ask that you replace @researchnutrition.com.au with @RNLabs.com.au.


HAVE YOU JOINED OUR PRACTITIONER FACEBOOK GROUP?

The RN Labs facebook practitioner group offers support and networking with other practitioners, where you can discuss industry matters, trending topics, and share case studies and clinic experiences.

You must be a RN Labs registered practitioner to be accepted into the group.



Upcoming Events

25 June 2019

Online Webinar

0Weeks0Days

The Secrets of Food Reactions

Understanding, Detecting & Addressing The Many Types of Food Reactions

In this comprehensive webinar, Clinical Nutritionist Warren Maginn will present the latest research, understanding and information regarding food allergies, intolerances and sensitivities.

TOPICS INCLUDE

  • What’s The Difference Between Allergy, Sensitivity & Intolerance?
  • What Are The Implications Of Each To Health?
  • Why Is Their Prevalence Increasing?
  • How Best To Test For Each?
  • Why Is There So Much Confusion?
  • What Can We Do About Them?
  • And A Live QnA with Warren

Register now to gain the most up-to-date information on food reactivity to apply to yourself and your clients.

27-28 July 2019

Freemantle, WA

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ACNEM Training

Courses in Sports Medicine, Mental Health, and Nutritional & Environmental Medicine

Sports Medicine: Join our experienced presenters for this one-day training on the interplay between exercise, health and performance. Hear from health experts who specialise in exercise and gain some evidence-based strategies to aid your patients in maintaining health while increasing performance.

Mental Health: Conditions to be covered include depression, anxiety and addiction. Our highly regarded presenters will bring their clinical experience and knowledge on the application of nutritional and environmental medicine in collaboration with conventional medical practice. Current scientific evidence for the effectiveness of treatment modalities will be presented including nutraceutical prescription, dietary manipulation, lifestyle modification and environmental factors, alongside the range of available testing and investigation options.

Foundations of NEM: The ACNEM ‘Foundations of Nutritional and Environmental Medicine (NEM)’ course is the entry-point for GPs and other healthcare professionals wanting to learn about Nutritional and Environmental Medicine.

15 September 2019

Sydney

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ATMS Functional GI Symposium

This year ATMS is pleased to host an ATMS Special Event, the Functional GI Symposium 2019 in Sydney on Sunday 15 September.

The ATMS 2019 Functional GI Symposium is a special event designed to provide a powerful educational focus with specialised, integrative, naturopathic trainings on the diagnosis and treatment of varied GI presentations.

Key areas being covered include:

  • Parasitic infections
  • Neurotrophic factors
  • Functional GI physical exam techniques
  • The latest in Microbiome research
  • IBD and Faecal Microbiota Transplantation
  • Microcirculation, pH, temperature and blood profile
  • Nutrition and lifestyle factors

24-27 October 2019

Sydney

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ACNEM Training

Courses in Women’s Endocrinology, Children’s Health, and Nutritional & Environmental Medicine

Women’s Endocrinology: Gain insight into functional endocrinology including thyroid, adrenal and sex hormones. Expert clinicians will present clinical insights and therapeutic recommendations on PCOS, thyroid disorders and menopause.

Children & Adolescent Health: Learn about specific nutritional requirements for children from pre-conception and infancy, through to puberty and adolescence.

Foundations of NEM: The ACNEM ‘Foundations of Nutritional and Environmental Medicine (NEM)’ course is the entry-point for GPs and other healthcare professionals wanting to learn about Nutritional and Environmental Medicine.


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