Depression and pain are some of the most common health disorders presented to both Allopathic and Holistic Health Practitioners in Australia. Furthermore Depression and pain are often intricately linked. In this case study, Anna, a 46-year-old woman had been experiencing lumbosacral pain and low moods for the past five years.
Anna had slipped on the floor and taken a minor fracture to her hip five years ago. Although the initial fracture had healed, a persistent ache continued in the lumbosacral region of her back. The patient identified that the lack of improvement in her pain had led to consistently low moods. The patient was consuming a varied and relatively healthy diet. |
Treatment
After the initial consult, the patient was prescribed 4 grams of DL-Phenylalanine per day for 2 weeks. The patient was also asked to increase fruit intake and drink a protein shake daily. |
Mechanism of Action
An essential amino acid, phenylalanine is converted to Phenylethylamine (PEA) which is believed to have amphetamine-like properties. Furthermore lower levels of PEA are often observed in depressed subjects. In terms of pain relief, it is thought that consumption of DL-Phenylalanine results in the up-regulation of the endogenous analgesia system – a pathway that when stimulated by chronic pain, may suppress certain pain receptive neurons, therefore resulting in pain reduction. |