Case Study: Huge Improvements in Anxiety and Focus

Despite his passion for his chosen field, he was still experiencing significant anxiety and an inability to focus. He also presented with sleep onset-insomnia (can’t wind down), preferred takeaway foods to home cooked ‘healthy’ meals, and poor water intake.

His practitioner managed to address dietary and behavioural areas with more awareness, mindfulness, and supplements, but ‘huge changes’ occurred with CDP-Choline. He reported improved concentration and focus and his comments were: “Wow, now I know what it feels like to be normal!”

Supplements included BioActive B-Complex with additional Sublingual B12 (DNA test revealed significant SNPs involving these vitamins); fish oil and Vitamin D.
Compounded formula GABA + 5HTP + Theanine with Lipotropex – this improved anxiety significantly for a few months.

Ongoing reluctance and poor compliance resulted in the return of anxiety. GI Defence + Lipotropex and CDP-Choline was then introduced, which “kicked in” within about 10 days. He continues to take all the above sporadically, except the Choline which he has recognised plays a major role in reducing anxiety and maintaining concentration/focus and learning capacity. He has also improved hydration and diet significantly, in line with reduced stress.

Gradual improvements were seen over several months, significant after 10 days of taking CDP-Choline.

He now has an absence of anxiety; improved concentration/focus and learning capacity; improved performance in both written and practical exams; and with reduced stress, his diet has improved significantly and he is willing to try new foods (especially vegetables).

His mother (a GP) is very pleased with the changes in her son after struggling for many years.

CDP-Choline Mechanism of Action CDP-Choline (otherwise known as Citicoline) has shown evidence of its cholinergic and neuroprotective actions and may be indicated in stroke rehabilitation, brain and spinal cord injuries, neurological diseases, eye conditions and to improve cognitive function. It is a specialised nucleotide form of Choline found naturally in the body, where it provides enhanced cholinergic and neuroprotective activities. Supplemental CDP Choline is a highly bioavailable form of Choline that is often used when nervous system supportive actions are required. CDP-Choline is rapidly absorbed, and highly bioavailable. It is metabolised in the gut wall and liver to choline and cytidine, and disperses throughout the body, passing through the blood-brain barrier and into the central nervous system.

CDP-Choline for the Brain

Continued administration has been shown to increase brain concentrations of the three major brain cell membrane phospholipids (phosphatidylcholine, phosphatidylethanolamine, and phosphatidylserine). Phospholipids play an essential role in synthesising neurotransmitters and regulating cell membranes’ proper function, which contributes to improved mental energy, increased acuity, and promotes healthy brain function.

CDP-Choline can provide a sparing effect on systemic choline reserves, and inhibit the breakdown of these key membrane phospholipids.

CDP-Choline acts on multiple neurotransmitter levels, and in particular, may increase the activity of Dopamine and Noradrenaline, within its neurotransmission supportive activities. Higher choline intake has been related to higher cognitive function. This includes reducing the cognitive deficit associated with ageing. Increases in glutathione synthesis may also be involved within these neuro-supportive activities.