Case Study: PMS Symptoms

Sylvia, a 26 year old female came into the initial consult with complaints of experiencing a strong case of Premenstrual Syndrome (PMS) to the point that it was affecting her life. Her symptoms consisted of extreme fatigue, a lack of focus, low moods and increased fluid retention.

The patient was also experiencing menorrhagia and menstrual cycles that would range between 3 weeks to 2 months. Therefore, further testing regarding hormonal function was also indicated.

Her diet consisted of high carbohydrate and low protein content. The patient often snacked on chocolate bars (2-3) throughout the day. She also drank 1 Litre of water per day.

The patient’s sleep patterns were also variable with sleep time consisting of 10pm-12 midnight to a wakeup time at 6am.


The patient was advised to reduce carbohydrate content and have more fulfilling protein rich meals such as eggs and vegetables. Chocolate bars were also replaced with nuts and fruit and overall water intake was increased to 1.5L. The patient was further advised to aim for 8 hours of sleep per night.

The patient was prescribed 280mg (2 caps) of Magnesium (as Magnesium Citrate) as well as 100mg (2 caps) of Pyridoxal-5-Phosphate per day.

Upon the next consult 4 weeks later, the patient noticed a marked improvement in her PMS symptoms. She noticed that her fluid retention and her lack of focus had improved and her depression had not been as severe. However she still experienced a reduction in energy before her menstruation.

Due to her menorrhagia further investigation into anaemia and other nutrient deficiencies is indicated. Furthermore, the results from hormonal panel testing will offer further treatment aims.

The treatment with the current nutrients will remain as research indicates a Magnesium and B6 combination is most successful over a number of months and not weeks.

Mechanism of Action

Magnesium Citrate

Magnesium has a stabilising effect on the nervous system due to its ability in controlling neuromuscular stimulation.

Pyridoxal-5-Phosphate (Vitamin B6)

Pyridoxal-5-Phosphate (the active form of vitamin B6) may support the reduction of PMS symptoms through a variety of mechanisms. Some major mechanisms are considered to be the B6 mediated increase in serotonin and dopamine. Serotonin and Dopamine are both neurotransmitters associated with strong effects on mood and energy. Moreover B6 also plays an essential role in the synthesis of fatty acids, thereby resulting in an indirect anti-inflammatory affect as well as further beneficial impact on nervous system function. B6 may also reduce fluid retention through its ability to decrease dopamine in the kidneys resulting in increased sodium excretion and fluid loss overall.

S QLD / N NSW Area Manager

Jessica Morland

Jess is a qualified Nutritionist with a Bachelor of Health Science in Nutritional Medicine. She believes that there is no one size fits all approach and is passionate about educating, inspiring and supporting clients and practitioners with a customised approach to healthcare. Specialties include preconception, pregnancy, post-natal and infant care. 

Jess is excited to build relationships, educate and share her knowledge with both retail and practitioners in South Queensland and Northern NSW.

Lauren Matich, BHSc (Nat.)

Lauren Matich

BHSc (Nat.)

Lauren is an NHAA accredited Clinical Naturopath with a Bachelor of Health Science. She is incredibly passionate about natural health and educating clients on the foundational importance of nutrition, lifestyle and stress management and believes complimenting these building blocks with nutraceutical support and functional testing often holds the key to optimal health and vitality. Lauren looks forward to supporting practitioners and clients in these key areas.

Specialties include supporting thyroid health, digestive disorders and mental health.